ABSTRACT
Objective:
It is known that infections caused by influenza viruses are important public health problems all over the world. In this study, the general features of influenza A (H1N1) virus infections were reviewed and the data of severe cases treated in intensive care unit were summarized.
Materials and Methods:
Demographic characteristics, clinical, laboratory and radiological findings of 12 patients with H1N1 who were followed up in the intensive care unit between 2009 and 2013 were evaluated retrospectively
Results:
The mean age was 33.9 years and 66% of the cases (n=8) were female. In 75% of the cases (n=9), an underlying cause such as respiratory, metabolic disease or pregnancy was detected. Eleven patients (92%) had acute respiratory distress syndrome, and ten patients (83%) had multi-organ failure and septic shock. Encephalitis was detected in two patients and peripheral circulatory defect was observed in two patients. The most common finding in the radiological examinations was infiltration of the lower and central zones of the lung. The length of intensive care stay was 1 to 18 days, and the mortality rate was 83% (n=10).
Conclusion:
The severity of pulmonary symptoms was the most important determinant of prognosis in patients with H1N1 and mortality increased in the presence of an underlying risk factor.
Keywords: Influenza A, intensive care, acute respiratory distress syndrome, mortality, pregnancy
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