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Patients with COVID-19 Pneumonia Treated with the Standard Protocol: Observational Results of Five Intensive Care Units
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Original Research
VOLUME: 18 ISSUE: 1
P: 1-13
March 2020

Patients with COVID-19 Pneumonia Treated with the Standard Protocol: Observational Results of Five Intensive Care Units

J Turk Soc Intens Care 2020;18(1):1-13
DOI: 10.4274/tybd.galenos.2020.57441
Hande Simten Demirel Kaya 1
Orkhan Mammadov 1
Lerzan Dogan 1
Zeynep Tuğçe Sarıkaya 1
İlkay Kısa Özdemir 1
Sevdinaz Rasimoğlu 1
Ararso Kedir Jima 1
Aylin İlksöz 1
Duygu Emine Güdük 1
Emir Kılınç 2
Seher İrem Kıran 2
Merve Şeker 2
Rehile Zengin 3
Ayşe Sesin Kocagöz 3
Mustafa Şener Yıldırım 5
Şaban Selçuk Dinçer 5
Fatma Elif Gülek 5
İbrahim Dikmen 5
Filiz Tüzüner 6
Murathan Yazıcı 6
Serkan Ünsal 6
Taner Ljama 6
İsmail Demirel 7
Işıl Köylüoğlu 7
Aykut Ayyıldız 7
Işıl Kesimci 7
Şahika Bolsoy Deveci 7
Canan Akıncı 8
Vildan Ersöz 8
Meltem Eren 8
Nilüfer Çeltik 8
Achmet Ali 9
İbrahim Özkan Akıncı 6
1. Acıbadem Sağlık Grubu Altunizade Acıbadem Hastanesi, Yoğun Bakım Kliniği, İstanbul, Türkiye
2. Mehmet Ali Aydınlar Acıbadem Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul
3. Zeynep Tuğçe Sarıkaya, Emir Kılınç, Seher İrem Kıran, Merve Şeker
4. Acıbadem Sağlık Grubu Altunizade Acıbadem Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, İstanbul, Türkiye
5. Mehmet Ali Aydınlar Acıbadem Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye
6. Acıbadem Sağlık Grubu Kozyatağı Acıbadem Hastanesi, Yoğun Bakım Kliniği, İstanbul, Türkiye
7. Acıbadem Sağlık Grubu Taksim Acıbadem Hastanesi, Yoğun Bakım Kliniği, İstanbul, Türkiye
8. Acıbadem Sağlık Grubu Maslak Acıbadem Hastanesi, Yoğun Bakım Kliniği, İstanbul, Türkiye
9. Acıbadem Sağlık Grubu Fulya Acıbadem Hastanesi, Yoğun Bakım Kliniği, İstanbul, Türkiye
10. İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
No information available.
No information available
Received Date: 29.05.2020
Accepted Date: 21.07.2020
Publish Date: 14.10.2020
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ABSTRACT

Objective:

The number of patients with COVID-19 has rapidly increased, thereby exceeding the capacities of health systems and causing serious losses in affected countries because of the rapid spreading potential, high virulence, and lack of vaccine and proven antiviral therapy. This may indicate the importance of protocol-based treatments in maintaining the treatment process accurately, with minimal errors. This study aimed to present the results of a protocol-based treatment prepared in accordance with the “Surviving Sepsis Campaign COVID-19 treatment guideline.”

Materials And Methods:

This retrospective and prospective study used data of five hospitals. Intensive care and treatment approaches were carried out in accordance with the “COVID-19 approach protocol” prepared according to the “Surviving Sepsis Campaign COVID-19 treatment guideline.”

Results:

A total of 1143 patients admitted to five hospitals were hospitalized with a prediagnosis of COVID-19, and 115 patients needed intensive care. Among them, patients without COVID-19 were excluded and the remaining 77 patients were evaluated. In this study, 9 (11.7%) of the 77 patients were lost. While the mortality rate did not differ by sex (p=0.661), the mean age of deceased patients was significantly higher (p=0.006). Considering their comorbidities, the mortality rates of patients with hypertension, chronic renal failure, and cancer were significantly higher (p=0.034, p=0.014, and p=0.007, respectively).

Conclusion:

The mortality rate in this series may suggest that the treatments performed in line with the “Survival in Sepsis Campaign COVID-19 treatment guideline” are useful. However, when the causes of mortality and morbidity were evaluated, good observation of neurological, infective, respiratory, and immune complications may be considered the main factor in reducing mortality and should be included in the guideline.

Keywords: COVID-19, ARDS, mechanical ventilation, prone position, sepsis, Turkey

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