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Effect of Gender on The Inflammatory Markers in COVID-19 Patients
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Original Research
VOLUME: 18 ISSUE: 1
P: 14-21
March 2020

Effect of Gender on The Inflammatory Markers in COVID-19 Patients

J Turk Soc Intens Care 2020;18(1):14-21
DOI: 10.4274/tybd.galenos.2020.29292
Özlem Polat 1
İlkay Anaklı 1
Gülçin Hilal Alay 1
Emre Çeliksoy 1
Verda Tuna 1
Günseli Orhun 1
Mehmet Kılıç 1
Mutlu Mercan 1
Figen Esen 1
Arif Atahan Çağatay 2
Perihan Ergin Özcan 1
1. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
2. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Enfeksiyon Hastalıkları Anabilim Dalı, İstanbul, Türkiye
3. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
4. İstanbul Üniversitesi, İstanbul Tıp Fakültesi
5. Reanimasyon Anabilim Dalı, İstanbul, Türkiye
6. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
7. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
8. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
9. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
10. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
11. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
12. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
No information available.
No information available
Received Date: 17.07.2020
Accepted Date: 03.09.2020
Publish Date: 14.10.2020
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ABSTRACT

Objective:

In November 2019, an outbreak of coronavirus disease-2019 (COVID-19) caused by SARS-CoV-2, a new type of coronavirus from Wuhan, China, was reported. The risk factors affecting mortality are still not clearly defined. This study aimed to determine the effect of gender on the inflammatory markers in COVID-19 patients who were admitted in the intensive care unit (ICU).

Materials and Methods:

Data of 90 COVID-19 patients who were admitted in the ICU of Istanbul Medical Faculty Hospital between March 18, 2020 and May 30, 2020, were retrospectively reviewed. Demographic, clinical, and laboratory records of the patients were obtained from electronic medical records, and male and female characteristics were compared.

Results:

The number of male patients (n=66) was higher than that of female patients (n=24). No significant difference was found between the clinical and demographic data of the patients. During admission to the ICU, interleukin-6 (IL-6) and ferritin levels of the male patients were significantly higher than those of the female patients. However, no significant difference was noted between the genders in terms of mortality.

Conclusion:

Among the COVID-19 patients in the ICU, the number of male patients was higher than that of the female patients, but gender had no significant effect on mortality. However, the presence of higher levels of inflammatory markers IL-6 and ferritin in the male patients may indicate a more severe disease in men.

Keywords: COVID-19, gender, inflammatory markers

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