Öz
Purple Urine Bag Syndrome (PUBS) is an uncommon clinical condition that is generally benign but rarely encountered by clinicians. It occurs due to the metabolism of tryptophan by intestinal bacteria, followed by hepatic conjugation. In the urine, bacterial sulfatase and phosphatase enzymes lead to the production of indigo and indirubin pigments, whose oxidation results in the characteristic purple discoloration.
We report the case of a 61-year-old female patient with known chronic obstructive pulmonary disease (COPD) and psoriasis. Due to inadequate oral enteral nutrition, a nutritional supplement was prescribed. Approximately seven hours after administration, purple discoloration of the urine bag was observed. Urine culture revealed growth of Proteus mirabilis, and the urine pH was 8.5. As the colony count was low, antibiotic therapy was not initiated. After discontinuation of the nutritional product, the urine color returned to normal.
Although PUBS is typically benign, catastrophic outcomes have been reported in delayed cases. Therefore, increasing awareness among healthcare professionals and ensuring early recognition and management are of vital importance.
Anahtar Kelimeler: purple urine bag syndrome, urinary tract infection, proteus mirabilis, oral nutrition support
Referanslar
- Khan F, Chaudhry MA, Qureshi N, Cowley B. Purple urine bag syndrome: an alarming hue? A brief review of the literature. Int J Nephrol. 2011;2011:419213. https://doi.org/10.4061/2011/419213
- Barlow GB, Dickson JAS. Purple urine bags. Lancet. 1978;311(8057):220-1.
- Kalsi DS, Ward J, Lee R, Handa A. Purple urine bag syndrome: a rare spot diagnosis. Dis Markers. 2017;2017:9131872. https://doi.org/10.1155/2017/9131872
- Saraireh M, Gharaibeh S, Araydah M, Al Sharie S, Haddad F, Alrababah A. Violet discoloration of urine: a case report and a literature review. Ann Med Surg (Lond). 2021;68:102570. https://doi.org/10.1016/j.amsu.2021.102570
- Hadano Y, Shimizu T, Takada S, Inoue T, Sorano S. An update on purple urine bag syndrome. Int J Gen Med. 2012;5:707-10. https://doi.org/10.2147/IJGM.S35320
- Neniwal VK, Swain S, Rulaniya SK, Hota D, Agarwal P, Yadav PK. Purple urine bag syndrome: an unusual manifestation of urinary tract infection, our experience at a tertiary care center. Curr Urol. 2023;17:125-9. https://doi.org/10.1097/CU9.0000000000000044
- Mahdi F, Larijani A. Purple urine bag syndrome: a unique clinical case and management considerations. BMC Nephrol. 2024;25:375. https://doi.org/10.1186/s12882-024-03708-6
- Tasi YM, Huang MS, Yang CJ, Yeh SM, Liu CC. Purple urine bag syndrome, not always a benign process. Am J Emerg Med. 2009;27:895-7. https://doi.org/10.1016/j.ajem.2009.01.030
- Popović MB, Medić DD, Velicki RS, Jovanović Galović AI. Purple urine bag syndrome in a home-dwelling elderly female with lumbar compression fracture: a case report. Healthcare (Basel). 2023;11:2251. https://doi.org/10.3390/healthcare11162251
- DeRon N, Legan C. Purple urine bag syndrome: a rare and surprising clinical presentation. Cureus. 2023;15:e33354. https://doi.org/10.7759/cureus.33354
- Sayın Kart J, Çevik B, Bombacı E, Saraçoglu KT. Purple bag urinary syndrome: a rare clinical condition. Bosphorus Med J. 2021;8(3):177-9. https://doi.org/10.14744/bmj.2021.18894
Telif hakkı ve lisans
Telif hakkı © 2026 Yazar(lar). Açık erişimli bu makale, orijinal çalışmaya uygun şekilde atıfta bulunulması koşuluyla, herhangi bir ortamda veya formatta sınırsız kullanım, dağıtım ve çoğaltmaya izin veren Creative Commons Attribution License (CC BY) altında dağıtılmıştır.
