Öz

Amaç:

Koronavirüs hastalığı-2019 (COVİD-19) ilişkili akut solunum sıkıntısı sendromu (ARDS) hastalarında kompliyans açısından ARDS fenotipleri tanımlanmıştır. Çalışmamızda COVİD-19 ilişkili ARDS hastalarında mekanik ventilasyon desteği ve sonuçları incelenmiştir.

Gereç ve Yöntem:

Retrospektif olarak planlanan çalışma, hesaplanan statik kompliyans değerine göre üç fenotip alt grup belirlenen COVİD-19 ilişkili ARDS hastalarında gerçekleştirildi [tip high (H) = Cstat <40 mL/cmH2O, tip light (L) = Cstat ≥50 mL/cmH2O ve tip intermediate (Int) =40≤ Cstat <50 mL/cm H2O]. Mekanik ventilasyon stratejisinin COVİD-19 ARDS fenotiplerinde mekanik ventilasyon süresi, yoğun bakım ünitesinde kalış süresi ve mortalite üzerindeki etkileri incelendi.

Bulgular:

Çalışma hastalarının COVİD-19 ARDS fenotipi açısından %72,3 tip H, %23,4 tip L ve %4,3 tip Int olduğu tespit edildi. Mekanik ventilasyon stratejisinin mekanik ventilasyon süresi (p=0,357), yoğun bakım ünitesinde kalış süresi (p=0,127) ve ölüm oranını (p=0,583) etkilemediği görüldü.

Sonuç:

COVİD-19 ilişkili ARDS hastalarında, kompliyans ilişkili fenotipten bağımsız koruyucu ventilasyon stratejisinin uygun olduğunu düşünüyoruz.

Anahtar Kelimeler: COVİD-19, akut solunum sıkıntısı sendromu, mekanik ventilasyon, fenotip

Referanslar

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Nasıl atıf yapılır?

1.
Kömürcü Ö, Küllaç S, Yılmaz A, Ülger F. Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome Phenotypes. Turk J Intensive Care. 2022;20:126-134. https://doi.org/10.4274/tybd.galenos.2022.30301