ÖZET

Amaç:

Bu çalışmanın amacı yoğun bakım ünitesinde (YBÜ) bulunan septik hastalarda eritrosit dağılım genişliğinin (RDW) prognostik değerini belirlemektir.

Gereç ve Yöntem:

Bu tek merkezli çalışmada, kritik olan sepsis hastalarının retrospektif bir analizi yer almaktadır. Hastaların demografik verileri, komorbiditeleri, YBÜ’ye kabuldeki RDW, 3. gün (RDW3) ve 7. gün RDW (RDW7) değerleri, Akut Fizyoloji ve Kronik Sağlık Değerlendirmesi-II (APACHE-II) skoru, hemodiyaliz ve invaziv mekanik ventilasyon (IMV) ihtiyacı sağ kalanlar ve vefat edenler arasında karşılaştırıldı. Ayrıca hastalar yüksek (>%14,5) ve normal (≤%14,5) RDW olarak iki gruba ayrıldı. YBÜ mortalitesi için bağımsız risk faktörlerini belirlemek üzere lojistik regresyon analizi yapıldı.

Bulgular:

Yüz iki septik hasta çalışmaya dahil edildi. Sağ kalanlar, vefat edenlere kıyasla daha düşük RDW’ye sahipti (YBÜ’ye kabuldeki RDW, RDW3 ve RDW7 değerleri, tümü için p<0,05). Yüksek RDW grubundaki hastalar normal RDW grubundaki hastalara göre daha yüksek APACHE-II skoruna, YBÜ’ye kabulde daha yüksek oranda septik şok varlığına, daha yüksek IMV ihtiyacına ve mortalite oranına sahipti (tümü için p<0,05). Bu çalışmada YBÜ’ye kabulde septik şok varlığı, RDW3 değeri ve IMV ihtiyacı mortalite için bağımsız risk faktörleri olarak bulundu.

Sonuç:

Bu çalışmada RDW3 değeri, kritik septik hastalarda mortalite ile anlamlı olarak ilişkili bulunmuştur ve YBÜ septik hastalarının prognozunu öngörmede önemli bir değere sahiptir.

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Yoğun Bakım Ünitesinde Septik Hastaların Sonuçları Üzerine Kırmızı Kan Hücresi Dağılım Genişliğinin Değerlendirilmesi: Retrospektif Bir Çalışma

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References