ÖZET
Amaç:
Bu çalışmada yoğun bakım ünitesinde (YBÜ) yatan kritik koronavirüs hastalığı-2019 (COVID-19) hastalarını demografik, klinik ve laboratuvar özellikleri açısından karşılaştırıp mortaliteye etkili olan faktörleri saptamayı amaçladık.
Gereç ve Yöntem:
Çalışmaya YBÜ’de COVID-19 nedeniyle yatan 445 hasta dahil edildi. Hastalar YBÜ’de takipleri sırasında mortalite gelişmeyenler ve mortalite gelişenler olarak iki gruba ayrılıp demografik, klinik ve laboratuvar özellikleri açısından karşılaştırıldı ve mortaliteye etki eden faktörler saptanmaya çalışıldı.
Bulgular:
İleri yaş, YBÜ’ye ilk yatıştaki yüksek Böbrek Hastalıkları: Küresel Sonuçların İyileştirilmesi (KDIGO) evresi ve Sıralı Organ Yetmezliği Değerlendirmesi (SOFA) skorları, yüksek nötrofil lenfosit oranı, yüksek D-dimer düzeyleri düşük bikarbonat (HCO3) değerleri, yüksek laktat dehidrogenaz (LDH) düzeyleri ve yüksek kreatinin düzeyleri YBÜ’de yatan kritik COVID-19 hastalarında mortalite için bağımsız risk faktörleri olarak saptandı. Özellikle YBÜ’ye başvuru esnasındaki KDIGO evresiyle mortalite arasındaki ilişki dikkat çekiciydi.
Sonuç:
YBÜ’de yatan kritik COVID-19 hastalarında yaş, ilk yatıştaki KDIGO ve SOFA skorları, nötrofil lenfosit oranı, D-dimer, HCO3, LDH ve kreatinin mortalite için bağımsız risk faktörleridir.
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