ABSTRACT

Objective:

The aim of this study was detect to infection source before the bloodstream infection (BSI) of patients with secondary BSI to examine the epidemiological features, sources of infection, prognosis and antibiotic resistance.

Materials and Methods:

Culture/antibiotic susceptibility results of all hospitalized patients were evaluated retrospectively. Age, gender, localization of infection, causative microorganism, antibiogram test results, time frame between primary and secondary BSI and prognosis of each patients with secondary BSI was investigated.

Results:

In a total of 1,584 patients, secondary BSI was detected in 200 patients, 158 (79%) of them in the intensive care unit and 42 (21%) of inpatient services. Median of time between primary and secondary bloodstream infections among specimen species were statistically insignificant (p=0.091). Urinary tract infection (37%) is the most common, followed by respiratory tract infections (31%), skin and soft tissue infections (18%), central nervous system infections (10%) and other infections (4%). Acinetobacter baumannii complex species had a resistance against more than 95% of antibiotics except aminoglycosides. Resistance to carbapenem group antibiotics was observed at a rate of 2% in Escherichia coli strains and the rate was found to be 35% in Klebsiella pneumoniae isolates. Methicillin resistance was found in 29% of Staphylococcus aureus and 90% of coagulase negative staphylococci and 25% of Enterococcus spp. were resistant to vancomycin.

Conclusion:

Knowing a source of infection in secondary bloodstream infections will lead to an identification of risk factors for infections and a description of infection control practices. It will reduce health expenditure as well as mortality rate.

Keywords: Secondary blood stream infections, nosocomial infections, antibiotic resistance

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Characteristics of Secondary Bloodstream Infections at the Region of İstanbul Northern Anatolian Association of Public Hospitals

ABSTRACT

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