The contain is extracted from the autumn crocus plant, colchicine that an antiinflammatory drug. The use of colchicine impairs mobilization and activation of neutrophil and supporting treating from some rheumatological diseases especially in childhood as familial mediterranean fever. Colchicine poisoning is rare but severe drug intoxication that can cause lifethreatening multiorgan failure at high doses. In this report, a girl who 15-year-old and has Familial Mediterranean fever was admitted to a hospital for ingesting 0.47 mg/kg colchicine. We treated her successfully receiving plasmapheresis and dialysis. The case of colchicine intoxication is a life-threatening problem requiring close monitoring. All the colchicine intoxication cases should be treated in the pediatric intensive care.

Keywords: Colchicine, adolescent, intoxication, pediatric intensive care