Intramuscular injection is themost commonly performed a basic medical intervention. Even though the first that comes to mind, damage to the sciatic nerve complications; problems related to soft tissue encountered. Instead of muscular injection to hipodermal area, it can lead to necrosis which fastest growing. In addition, an excessive immune response to the drug can be seen; it is named that toxic epidermal necrolysis. In this article, we presented a toxic epidermal necrolysis case who died due to severe sepsis and multiple organ failure after intramuscular injection of nonsteroidal anti-inflammatory drug.

Keywords: Intramuscular injection, nonsteroidal anti-inflammatory drug, toxic ep idermal necrolysis, sepsis, multiple organ failure